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Did you know?

Studies show up to

of patients on synthetic L-T4 monotherapy may have persistent hypothyroidism symptoms despite normal TSH levels1

Therapy brands were not specified in the studies.1

What is NP Thyroid®?

NP Thyroid® is a naturally-derived* desiccated thyroid extract (DTE) therapy option that can help you individualize your approach to treating your hypothyroidism2

NP Thyroid® tablets are tan in color and are debossed
with the letters AP.

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Image does not represent the actual size of the NP Thyroid® tablet. The number debossed on the tablet will vary by strength.

Why NP Thyroid®?
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    Naturally-derived* therapy containing T4 and T3
    in one tablet2

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    Only 3 inactive ingredients2

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    Available in 5 dose strengths for easy titration to achieve the necessary therapeutic range2

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    Works quickly (2 to 3 weeks)2

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    Dye-free and contains no ingredient made from a gluten-containing grain (wheat, barley, or rye)2

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    Uncoated tablet for oral administration2,3

  • Patients section two icon1

    Naturally-derived* therapy containing T4 and T3
    in one tablet2

  • Patients section two icon4

    Works quickly (2 to 3 weeks)2

  • Patients section two icon2

    Only 3 inactive ingredients2

  • Patients section two icon5

    Dye-free and contains no ingredient made from a gluten-containing grain (wheat, barley, or rye)2

  • Patients section two icon3

    Available in 5 dose strengths for easy titration to achieve the necessary therapeutic range2

  • Patients section two icon6

    Uncoated tablet for oral administration2,3

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Active Pharmaceutical Ingredient (API) and finished product manufactured in FDA-regulated and -inspected facilities3

What does NP Thyroid® treat?

NP Thyroid® is used as a replacement or supplemental therapy in patients with hypothyroidism of various causes, including3:

  • Congenital hypothyroidism
  • Myxedema
  • Hypothyroidism in patients of any age (children, adults, the elderly) or state (including pregnancy)
  • Primary hypothyroidism resulting from functional deficiency
  • Primary atrophy
  • Partial or total absence of the thyroid gland
  • The effects of surgery, radiation, or drugs with or without the presence of goiter
  • Secondary (pituitary) or tertiary (hypothalamic) hypothyroidism
  • May be used as a TSH suppressant, in the treatment or prevention of various types of euthyroid goiters, including thyroid nodules, subacute or chronic lymphocytic thyroiditis (Hashimoto’s), multinodular goiter, and in the management of thyroid cancer
Dosage and how to take NP Thyroid®

The dosage of thyroid hormones is specific to each individual and must be individualized according to licensed prescriber, patient responses, and laboratory findings2

Available in the
following dosage levels2:

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  • Available in multiple strengths for easy titration to achieve the necessary therapeutic range2
  • Adequate therapy usually results in normal TSH and T4 levels after 2 to 3 weeks of therapy2
  • Readjustments of thyroid hormone dosage should be made within the first 4 weeks of therapy, after clinical and laboratory evaluations by your healthcare provider2

It is important to take NP Thyroid® exactly as your healthcare provider prescribed to help you manage your hypothyroidism

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    Take NP Thyroid® daily, at the same time, with an 8 oz glass of water or as otherwise directed by your healthcare provider.2,4

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    Take NP Thyroid® 4 hours before or after taking cholestyramine.2

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    Take NP Thyroid® on an empty stomach, at least 30 to 60 minutes before consuming any food. This means no eating or drinking anything other than water! Fasting increases absorption.2,4,5

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    Soy can affect the absorption of NP Thyroid®. Regular consumption of soy-containing foods may require dose adjustments.2

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Get NP Thyroid®

Use the tools below to help find a healthcare provider you can speak with about NP Thyroid® and also to find ways to purchase NP Thyroid® at an affordable price.

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Find a healthcare provider

Use telemedicine to connect with a thyroid specialist online or locate a healthcare provider near you.

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Find savings

Get NP Thyroid® consistently and conveniently with free home delivery and pricing as low as $25 per month.

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Sign up to download a helpful patient brochure that answers common questions about hypothyroidism and NP Thyroid®.
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Get advice from experts

Get advice, tips, and information on living with hypothyroidism from our expert bloggers. Topics include nutrition, exercise, well-being, and more.

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Find more resources

Visit the Resources page for more support in the form of checklists, downloads, and other helpful information.

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Note that DTE products, including NP Thyroid®, have not been reviewed by the FDA for safety or efficacy.

IMPORTANT RISK INFORMATION, INCLUDING BOXED WARNING & INDICATIONS
Important Risk Information 

Drugs with thyroid hormone activity, alone or together with other therapeutic agents, have been used for the treatment of obesity. In euthyroid patients, doses within the range of daily hormonal requirements are ineffective for weight reduction. Larger doses may produce serious or even life-threatening manifestations of toxicity, particularly when given in association with sympathomimetic amines such as those used for their anorectic effects.
  • NP Thyroid® is contraindicated in patients with uncorrected adrenal insufficiency, untreated thyrotoxicosis, and hypersensitivity to any component of the product.
  • In the elderly and in patients with cardiovascular disease, NP Thyroid® should be used with greater caution than younger patients or those without cardiovascular disease.
  • Use of NP Thyroid® in patients with diabetes mellitus or adrenal cortical insufficiency may worsen the intensity of their symptoms.
  • The therapy of myxedema coma requires simultaneous administration of glucocorticoids.
  • Concomitant use of NP Thyroid® with oral anticoagulants alters the sensitivity of oral anticoagulants. Prothrombin time should be closely monitored in thyroid-treated patients on oral anticoagulants.
  • In infants, excessive doses of NP Thyroid® may produce craniosynostosis.
  • Partial loss of hair may be experienced by children in the first few months of therapy but is usually transient.
  • Adverse reactions associated with NP Thyroid® therapy are primarily those of hyperthyroidism due to therapeutic overdosage.
  • Many drugs and some laboratory tests may alter the therapeutic response to NP Thyroid®. In addition, thyroid hormones and thyroid status have varied effects on the pharmacokinetics and actions of other drugs. Administer at least 4 hours before or after drugs that are known to interfere with absorption. Evaluate the need for dose adjustments when regularly administering within one hour of certain foods that may affect absorption.
  • NP Thyroid® should not be discontinued during pregnancy, and hypothyroidism diagnosed during pregnancy should be promptly treated.

Indications

NP Thyroid® (thyroid tablets, USP) is a prescription medicine that is used to treat a condition called hypothyroidism from any cause, except for cases of temporary hypothyroidism, which is usually associated with an inflammation of the thyroid (thyroiditis). It is meant to replace or supplement a hormone that is usually made by your thyroid gland.

NP Thyroid® is also used in the treatment and prevention of normal functioning thyroid goiters, such as thyroid nodules, Hashimoto’s thyroiditis, multinodular goiter, and in the management of thyroid cancer.

Revised 10/2023